Pathogenesis of Medical Conditions Causing Mania

A diagram from The Calgary Guide to Understanding Disease breaks down the pathogenesis of medical conditions that cause either mania or mania-like episodes. These conditions include bipolar disorder, multiple sclerosis, B12 deficiency, altered thyroid activity, and corticosteroid use. Per the guideline, mania is outlined as at least 1 week of abnormal and persistent elevated, extensive, or irritable behavior, as well as abnormal and persistent higher amounts of goal-directed activity or energy.

Reference: Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis. The Calgary Guide to Understanding Disease. Published November 14, 2017. Accessed June 27, 2022.

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