Reviewing Progress in the Research of Bipolar Disorder

In this paper, researchers review current areas of progress in the research of bipolar disorder from a biological and therapeutic perspective. This includes findings of genes that are at risk and the implications, with a particular focus on voltage-gated calcium channel involvement in the disease process and as a drug target. The second area explored focuses on new technologies and the increasing perception of the bipolar phenotype being more complex and nuanced than just regular manic and depressive episodes. The researchers point out that bipolar disorder shows the transformation of psychiatry through current neuroscience, genomics, and digital tactics.

Reference: Harrison PJ, Geddes JR, Tunbridge EM. The Emerging Neurobiology of Bipolar Disorder. Trends Neurosci. 2018;41(1):18-30. doi:10.1016/j.tins.2017.10.006

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